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Drug Combination

Optimization of Drug Combination

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    Basgenbio presents new combination of drugs with
    maximum efficacy at the same time as minimum adverse drug reactions
    through drug-drug interaction analyses.

    Framework

    Leveraging years’ worth of Prescription Data, Mendelian Randomization, Network Analysis, and AI Algorithm, optimum drug combinations are suggested.
    It recommends the best drug combinations by integrating drug efficacy, possible adverse drug reactions, and marketability.

    COMBI FINDER

    Simultaneous considerations in marketability and combined drug effects are implemented through analysis of prescription data (from 2 to N drug combination therapies).

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    Recommendations based on target diseases
    and active drug ingredients.

    • CANDIDATE A

      INGRED 1

      INGRED 2

      INGRED 3

    • CANDIDATE B

      INGRED 4

      INGRED 5

      INGRED 6

    • CANDIDATE C

      INGRED 7

      INGRED 8

      INGRED 9

    Recommendation of optimized combination structures of drug compounds.

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    Confirmation of existing combination drugs
    (fixed-dose combinations of 2 to N drugs).

    DEEPCT

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    Comparison of clinical outcome between no treatment, monotherapy, or combination therapy groups

    Example of Visualized Results

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    Credit

    Project Manager
    Jungeun Kim
    AI algorithm Developer
    Jiyeon Kim, Suhan Cho
    Project Leader
    Suhan Cho
    Network analysis
    Jiyeon Kim, Yujeong Shim