Marker Discovery for Drug Responders/Non-Responders
Basgenbio predicts drug responders and non-responders
by developing algorithms for drug effectiveness, applicable to
personalized medicine development.
Framework
Identifying biomarkers that classify drug responders and non-responders is an essential technology for developing personalized treatments.
Case of Drug Response Biomarker Discovery (Antidepressants)
* RCT : Randomized Clinical Trial
Response Marker Interaction GWAS
Comparative Analysis of Antidepressant Responders vs. Non-Responders
Exploration of Antidepressant Resistance-Related Markers
Resistant, Non-Resistant Interaction Filtering
Final set of 27 markers established.
Classifier Performance
Comparison and Performance Analysis of Resistance Group Marker Gene Scores